Your next customer may research you in ChatGPT, compare you with two other suppliers inside a procurement tool, and send a purchase order that software drafted. That shift explains why most lists of B2B eCommerce trends for 2026 lead with AI: agentic commerce, hyper-personalization, AI-led discovery and AI inside the ERP. They depend on one thing most trend lists skip: whether AI can read your ERP data, and the product data built on it, accurately, safely and in real time. This guide covers what each trend changes for distributors and manufacturers, which numbers hold up, and what to fix in the next 90 days. For a distributor, that means some orders will come from a customer’s software rather than from a person clicking through your portal.